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. 2021 Dec 10;15:787475. doi: 10.3389/fnbeh.2021.787475

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Copyright © 2021 Dickerson, Murphy, Urban, White and VandeVord.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decreased levels of GFAP were observed in the hippocampus 52 weeks following blast injury. (A) Representative images of GFAP (green) and DAPI (blue) obtained from the hippocampus region of the brain. Magnification is at 20x and scale bar = 50 μm. (B) Decreased positive GFAP signal (area fraction) was observed in the CA2 sub-region of the hippocampus in blast animals compared to shams. Decreases in the amount of GFAP+ astrocytes were observed in the CA1 and CA2 sub-regions in blast animals. *p < 0.05. Data is represented as Mean ± SEM. DAPI, 6-diamidino-2-phenylindole.