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. 2021 Dec 10;8:778283. doi: 10.3389/fmed.2021.778283

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Copyright © 2021 Qiu, Zhao, Zhang, Wang, Wang, Nie, Chen and Cheung.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparisons of the retinal microvasculopathy (FAZa, FAZp, FAZ-CI, and VD in SCP and DCP) among the normal control (healthy subjects), DM (no DR), NPDR and PDR groups. The bar charts show the comparison results of the VD in SCP (A), VD in DCP (B), FAZa in SCP (C), FAZa in DCP (D), FAZp in SCP (E), FAZp in DCP (F), FAZ-CI in SCP (G), and FAZ-CI in DCP (H) in eyes with normal control (healthy subjects), DM (no DR), NPDR, and PDR. FAZ, foveal avascular zone; FAZ-CI, FAZ circularity index; VD, vessel density; SCP, superficial capillary plexus; DCP, deep capillary plexus; DM, diabetes mellitus; DR, diabetic retinopathy; NPDR, non-proliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy.