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. 2021 Dec 10;8:778283. doi: 10.3389/fmed.2021.778283

Figure 5.

Figure 5

Relationship between the parameters of retinal microvasculopathy (FAZa, FAZp, FAZ-CI, and VD in SCP and DCP) and ganglion cell degeneration (the relative mean thickness of RNFL, GCL, and GCC). After controlling the age, sex, and duration of DM and hypertension with Spearman's partial coefficient correlation analysis, the rmtGCL was negatively correlated with the FAZa in SCP (r = −0.34, P = 0.002) and DCP (r = −0.23, P = 0.033), and FAZp in SCP (r = −0.37, P = 0.001) and DCP (r = −0.32, P = 0.003), but positively correlated with VD in SCP (r = 0.26, P = 0.016) and DCP (r = 0.28, P =0.012), and FAZ-CI in DCP (r = 0.31, P = 0.006). The correlations between rmtRNFL, rmtGCL and rmtGCC with the FAZa in SCP (A), FAZa in DCP (B), FAZp in SCP (C), FAZp in DCP (D), FAZ-CI in SCP (E), FAZ-CI in DCP (F), VD in SCP (G) and VD in DCP (H) were described. The rmtRNFL was negatively correlated with FAZ-CI in SCP (r = −0.23, P = 0.038). The rmtGCC was positively correlated with SCP vessel density (r = 0.24, P = 0.029). FAZ, foveal avascular zone; FAZ-CI, FAZ circularity index; VD, vessel density; SCP, superficial capillary plexus; DCP, deep capillary plexus; rmtRNFL, relative mean thickness of retinal nerve fiber layer; rmtGCL, relative mean thickness of ganglion cell layer; rmtGCC, relative mean thickness of ganglion cell complex; DM, diabetes mellitus.