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. 2021 Nov 20;298(1):101440. doi: 10.1016/j.jbc.2021.101440

Figure 3.

Figure 3

ARHGEF17 overexpression increases cell proliferation and migration.A, LAP0297 cells were transfected with EGFP or EGFP-GEF17, which was revealed by Western blot from with anti-GEF17 antibodies. Graph represents the mean ± SEM; n = 3; ∗∗p < 0.01; t test. B, proliferation assay of LAP0297 cells (EGFP or EGFP-GEF17) stimulated with 10% FBS. Graph represents the mean ± SEM, n = 4. ∗∗∗p < 0.001, ∗∗p < 0.01, ∗p < 0.05; t test. C, migration assay of LAP0297 cells (EGFP or EGFP-GEF17) stimulated with 5 μM LPA. Graph represents the mean ± SEM; n = 3. ∗∗∗p < 0.001, ∗∗p < 0.01; t test. The scale represents 500 μm. EGFP, enhanced GFP; FBS, fetal bovine serum; LPA, lysophosphatidic acid.