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. 2021 Dec 17;14(12):1323. doi: 10.3390/ph14121323

Table 2.

Structures of sEHI 11a–c and their microsomal stabilities [19].

graphic file with name pharmaceuticals-14-01323-i001.jpg

Cmpd
#		 R Microsomal Stability 1
Human Mouse
% Remaining at 1 h
11a CH3 70 10
11b F 77 36
11c Cl 89 60

1 Percentage of remaining compound after 60 min of incubation with human and mouse microsomes obtained from Tebu-Xenotech in the presence of NADPH at 37 °C. See Materials and Methods for further details.