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Schematic representation of potential neuroprotective pathways for DHA in the ENS. Illustration depicting a proposed model for DHA-mediated enteric neuroprotection in the Thy1-αSyn mouse model. Abbreviations: DHA, docosahexaenoic acid; DHEA, docosahexaenoyl ethanolamide; GLP-1, glucagon-like peptide-1; GPR120, G-protein coupled receptor 120; Nrf2, nuclear (erythroid-2) related factor-2; TH, tyrosine hydroxylase.
