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. 2021 Dec 7;13(12):2102. doi: 10.3390/pharmaceutics13122102

Table 4.

Name list of the nanoformulations and their corresponding therapeutic applications.

S. No. Name of the Nanoformulation Formulation Ingredients and Method Application References
1 Cur@CRN Nanocomposites containing Cur and ι-Carrageenan using emulsion technique Enhanced stability, oral bioavailability, antioxidant and anti-inflammatory effects [207]
2 CUR-Gel-HAp Encapsulation of curcumin into the hydrophilic network of gelatin (Gel) and hydroxyapatite (HAp) by colloidal suspension Enhanced cytotoxicity towards human lung cancer cells (A549) [9]
3 Nanocurcumin Nanomicelle with an average size of 50 nm containing curcumin Enhanced antioxidant and anti-inflammatory effects against LPS-induced coliform mastitis in rat model [208]
4 Curcumin nanoparticle Curcumin loaded in poly lactic-co-glycolic acid nanoparticles with an average size of ~90 ± 10 nm by green surfactant-based synthesis Enhanced solubility, photo-stability, antibiofilm activity and cytotoxicity towards HepG2 cells [209]
5 CUR-loaded NC Curcumin-loaded polymeric nanocapsules Enhanced antiangiogenic, non-teratogenic and antioxidant effects in chick embryo model. [210]
6 MSN-HA-C Curcumin loaded in nanohybrid composed of mesoporous silica nanoparticle (MSN) and hyaluronic acid (HA) with an average size of ~75 nm In vivo and in vitro anti-breast cancer activity [211]
7 Fe@Au-CU-CS-FA NP’s Nanoencapsulation comprised of folic acid, gold, curcumin, chitosan and iron synthesised by microemulsion method Cytotoxic effect on lung cancer cells [212]
8 SD-CUR A core–shell solid dispersion composed of curcumin-loaded micelles self-assembled from disodium glycyrrhizin (Na2GA), coated with pectin and tannic acid Enhanced bioavailability and antihyperlipidemic activity [213]
9 SNLYZ-Cur The nanoconjugate SNLYZ-Cur composed of curcumin surface-conjugated on self-assembled lysozyme nanoparticle with an average size of ~120 nm Antibacterial, antioxidant and anticancer activity against multiple cancer cell lines such as HeLa, MCF-7, MDAMB-231 and MG 63 [214]
10 Cur-CasNPs Encapsulation of curcumin in casein nanoparticles Enhanced bioavailability and anticancer activity against MCF-7 cell lines [215]
11 CDD-CANPs Encapsulation of curcumin diethyl disuccinate (CDD) in chitosan–alginate nanoparticles (CANPs) High chemical stability upon UV light exposure, fivefold enhanced bioavailability and anticancer activity against HepG2 cell lines [216]
12 Cur NE-CLA-n-3FA Nanoemulsions containing curcumin stabilized with mono- and diacylglycerols structured with conjugated linoleic acid (CLA) and n-3 fatty acids (n-3FA) Greater bioavailability [217]
13 Cur-C3-CNPs Nanoparticle composed of curcumin-C3 complex (curcumin, demethoxycurcumin and isdemethoxycurcumin) encapsulated in chitosan Antioxidant and antibacterial activity [12]
14 CLL Nanoliposomes (formulated from salmon, rapeseed and soya lecithin) comprising of curcumin encapsulated in chitosan Increased bioavailability and anticancer activity against MCF-7 breast cancer cell lines [218]
15 Cur-BR liposome Nanoliposome containing curcumin and bromocriptine synthesized by thin-film method In vitro anticancer activity against lung cancer cells by induction of apoptosis [219]
16 LRA-CS-CUR hydrogel A composite hydrogel containing lotus root amylopectin (LRA)-chitosan (CS) in the ratio of 3:2 at pH 4.0 with an average size of 410.3 nm Enhanced stability in stomach and sustained release in small intestine [220]
17 Chitosan-PEG-Cur-hydrogel Hydrogel comprising of chitosan, polyethylene glycol and curcumin using microwave technology at frequency of 2450 MHz, 500 Watt and 120 s time. In vivo open incision wound healing activity [221]