Figure 4.
Ex vivo and in vivo colonic adhesion profiles of PT-LbL Lipo. (A) Residual fluorescence in UC rat colons ex vivo after incubation with various C6 formulations for 2, 4, and 6 h at 37 °C. (B) Quantification of fluorescence intensity in these colon tissues; Statistical significance was assessed (* p < 0.05). (C) After 12 h post-administration of various C6 formulations, UC mice were sacrificed and the colon tissues were collected. Fluorescence permeation in frozen sections were observed by CLSM. Green and blue represented the permeated C6 and cell nucleus stained by DAPI.