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. 2021 Dec 8;22(24):13211. doi: 10.3390/ijms222413211

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Developmental-related transcriptomic roadmaps in the human fetal brain and glioblastoma samples. Cell maps built with human prenatal telencephalic cells (A) and glioblastoma cells from whole-tumor samples (B–D) or enriched by CD133-positive selection; a population named glioma stem-like cells (GSC) in C. GPC cluster (orange, (A,B)), oligo-lineage cluster (violet, (A,B)), astrocyte cluster (coral, (A,B)), tRG cluster (green, (A,B)) and interneuron cluster (blue, (A,B)), but also a non-defined intermediate population (grey, (B); adapted from [74].