Table 2.
Therapeutic anti-Inflammatory agents.
| DRUG | ACTION | TRIAL |
|---|---|---|
| Aspirin | Inhibitor of COX | Coronary Microvascular Angina Trial (CorMicA) [102] |
| Colchicine | Inhibition of NLRP3 inflammasome | COLCOT Trial [103] |
| Anakinra | Monoclonal antibody against IL-1 Receptor | Ikonomidis et al. [104] |
| Canakinumab | monoclonal antibody against IL-1-beta | CANTOS Trial [5] |
| Tocilizumab | IL-6 Receptor Inhibitor | Holte et al. [105] |
| Etanercept | TNF-α antagonists | ENTRACTE Trial [106] |
| Adalimumab | TNF-α antagonists | ENTRACTE Trial [106] |
IL: interleukin; TNF: tumor necrosis factor; NLRP3: NOD-like receptor protein 3; COX: cyclooxygenase.