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. 2021 Dec 5;13(12):2089. doi: 10.3390/pharmaceutics13122089

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Influence of agrimoniin on respiration during oxidation of succinate and NAD-dependent substrates. Respiration supported by succinate (5 mM) oxidation (A) and glutamate (4 mM) plus malate (2 mM) oxidation (B) in control and in the presence of agrimoniin (50–100 µM); effect of agrimoniin in different concentrations on respiration rates in ADP (200) and DNP (50 µM) –stimulated states (C); respiratory control index (D). The respiratory control index was calculated as the ratio of respiration in the course and after ADP phosphorylation. Asterisk (*) indicates values that differ significantly from the control values (p < 0.05).