Figure 3.

The effect of food restriction on the levels of cyclin-dependent kinase 5 (CDK5), its activator, p35, Hsp90, and FKBP51 levels in the rat cortex during aging. Relative protein levels of the CDK5 (A), p35 (B), Hsp90 (C), and FKBP51 (D) were determined by Western blot analysis in rats fed ad libitum (AL) (gray bars) or subjected to food restriction (FR) (black bars). Data are presented as the mean ± SEM of fold changes relative to the values obtained in control, 6-month-old AL animals (n = 6). * p < 0.05 vs. 6-month-old rats; # p < 0.05 vs. age-matched AL rats.