Table 7.

Predicted amino acid substitution in the EF protein.

lef Mutation	Predicted Amino Acid Substitution in the Unprocessed LF	Domain of EF	Number of Strains
539A→G	D→G180	PA-binding domain	13
600C→T	- *		71
832A→G	K→E278	PA- binding domain	4
876G→A	-		1
953T→C	I→T318	CA	17
1140C→T	-		1
1329A→T	E→D443	CB	1
1400A→G	E→G467	CB	1
1971C→T	-		1
2081T→C	V→A694	Spiral domain	3
2129A→C	H→P710	Spiral domain	3
2264G→T	R→M755	Spiral domain	1
2367T→A	N→K789	Spiral domain	4

* synonymous mutation.