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. 2021 Dec 18;14(24):7859. doi: 10.3390/ma14247859

Table 7.

Ni release from NiTi archwire or orthodontic devices with NiTi wire on exposure to saliva or biological fluid.

Concentration Unit Time (Days) Type of Sample Technique Solution/V for Exposure pH Author Recalculated Conc.
(µg/cm2/week)
11.77 ppb/day 1 Orthodontic devices with NiTi wire HR-ICP/MS A. sal.
50 mL
6.75 [94] 3.56
10.83 ppb/day 6 3.27
6.13 ppb/day 7 1.85
3.38 ppb/day 14 1.02
835.1 ppb/day 1 3.5 252
459.5 ppb/day 6 139
138.9 ppb/day 7 42.0
61.9 ppb/day 14 18.7
4.29 ppb 1 Orthodontic devices with NiTi wire AAS A. sal.
100 mL
6.75 [95] 1.13
8.41 ppb 7 0.32
2.76 ppb 14 0.052
1.58 ppb 21 0.02
0.70 ppb 28 0.0066
0.62 ppm 1 Orthodontic devices with NiTi wire A. sal.
25 mL
6.69 [88] 0.075
0.234 ppm 4 0.0071
0.395 ppm 7 0.0068
0.452 ppm 9 0.0061
0.669 ppm 14 0.0058
0.917 ppm 21 0.0053
1.267 ppm 28 0.0055
0.44 µg/L 1 NiTi wire ICP-MS A. sal.
100 mL
6.5 [3] 0.39
0.49 µg/L 2 0.22
0.4 µg/L 3 0.12
0.37 µg/L 7 0.047
0.33 µg/L 14 0.021
0.28 µg/L 21 0.012
0.00122 ng/mm2 7 NiTi wire AAS HBBS / [110] 0.000122
0.00160 ng/mm2 14 0.00008
0.00204 ng/mm2 30 0.00005
Cca. 5 ng/L 14 NiTi wire ICP-OES 0.9 M NaCl
25 mL
/ [111] 0.000043
Cca. 11 ng/L 30 0.000047
Cca. 20 ng/L 60 0.000043
Cca. 1 µg/cm2 1 NiTi wire AAS A. sal.
2 mL
3.75 [36] 7.0
Cca. 1 µg/cm2 3 2.3
Cca. 2.5 µg/cm2 7 2.5
Cca. 3 µg/cm2 14 1.5
Cca. 5 µg/cm2 28 1.25
Cca. 0.1 µg/cm2 1 6.25 0.7
Cca. 0.3 µg/cm2 3 0.7
Cca. 0.8 µg/cm2 7 0.8
Cca. 1.9 µg/cm2 14 0.95
Cca. 2.0 µg/cm2 28 0.5