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. 2021 Dec 10;8:784429. doi: 10.3389/fnut.2021.784429

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Copyright © 2021 Minuzzi, Seelaender, Silva, Cunha, Deus, Vasconcellos, Marqueze, Gadotti, Baena, Pereira, Krüger, Amaral, Pinho and Lira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BDNF and BDNF-related ratios for patients with COVID-19 in relation to clinical outcome. Values expressed as mean with 95% Confidence Interval for patients that were hospitalized without intensive care (Non-ICU), patients admitted to the intensive care unit and discharged (ICU-survivor) and patients who died (ICU-death), including: BDNF (A–C), BDNF/adiponectin ratio (D–F), and BDNF/leptin ratio (G–I) related to body index mass (BMI), sex and age, respectively. Dashed box presents linear regression curve of adiponectin (J), leptin (L), and adiponectin/leptin ratio (M) as dependent variable (Y axis) with outcome as independent variable (X axis). Significance: *p < 0.05; **p < 0.01.