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. 2021 Dec 11;22(24):13335. doi: 10.3390/ijms222413335
AFC Ammonium Ferric Citrate
ALK Anaplastic lymphoma kinase
ARE AU-rich element
ASCL4 achaete-scute family bHLH transcription factor 4
CBS cellular cystathionine-beta-synthase
CCK-8 cell counting kit-8
circRNA circular RNA
DEGs differential expressed genes
EGFR epithelial growth factor receptor
ETC electron transport chain
FAK focal adhesion kinase
FSP1 ferroptosis suppressor protein 1
GCL glutamate-cysteine ligase
GCLC γ-cysteine ligase catalytic subunit
GCO Global Cancer Observatory
GEO Gene Expression Omnibus
GGC γ-Glutamylcysteine
GGT γ-glutamyl transpeptadase
Gly Glycine
GOT1 cytosolic aspartate aminotransaminase
GPX4 glutathione peroxidase 4 (phospholipid hydroperoxidase)
GSEA gene set enrichment analysis
GSH glutathione
GSS glutamate synthetase
GSSG L-Glutathione Oxidized
H&E staining hematoxylin and eosin staining
HME cells human mammary epithelial cells
HO-1 Heme Oxygenase-1
HP haptoglobin
IHC immunohistochemistry
IREB2 iron-responsive element-binding protein 2
Keap1 kelch-like ECH-associated protein 1
KEGG Kyoto Encyclopedia of Genes and Genomes
KRAS kirsten rat sarcoma viral oncogene
LncRNA long non-coding RNA
LUAD Lung adenocarcinoma
LUSC Lung squamous cell carcinoma
MDA malondialdehyde
METTL3 methyltransferase-like protein 3
MREs microRNA response elements
mTORC1 mTOR complex 1
NAC N-Acetyl-L-cysteine
NFS1 Cysteine desulfurase NFS1
NRF2 Subcellular localization of nuclear factor E2-related factor 2
NSCLC non-small cell lung cancer
PCD programmed cell death
PD-1/PDL-1 programmed cell death protein-1/programmed cell death protein-Ligand 1
ROS reactive oxygen species
SLC7A11 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
SLC3A2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
SOD superoxide dismutase
TCA tricarboxylic acid cycle
TCGA The Cancer Genome Atlas
TFRC transferrin receptor
TKIs tyrosine kinase inhibitors
TXN2 thioredoxin 2
VEGFA vascular endothelial growth factor A
xCT cystine/glutamate transporter
3′-UTR′ 3′-untranslational region