Table 1.

Criteria for inclusion according to the PICOS method.

Definition	Inclusion Criteria	Exclusion Criteria
Population	Adult (≥16 and ≤40 years old) football players (i.e., Association football) of any level Both male and female Not having suffered a severe injury the previous 2 years	Studies including different cohorts of athletes apart from football players (e.g., basketball, volleyball, handball) in which no sub-analysis by sport was performed
Intervention	Exercise or training-based interventions lasted at least 4 weeks, performed twice a week	Interventions performed with exogenous modalities (i.e., bracing, taping, etc.) or those exercise-based interventions lasting less than 4 weeks.
Comparator	Control group data if available (although not necessarily)	No exclusion criteria by comparator
Outcome	Either contact or non-contact ACL injury incidence or rate of injury Test measurements evaluating any modifiable risk factor (i.e., potentially targeted by exercise-based interventions) previously reported to have an influence in ACL injury [23,26,27,46], such as biomechanical, neuromuscular and/or physical tests (e.g., biomechanics of landing or cutting actions, H/Q ratio, balance measures, ankle or hip range of motion, etc.)	Overall injury incidence not explicitly reporting ACL type injuries Test measurements evaluating non-modifiable risk factors (e.g., anatomical)
Study design	Randomised-controlled trials Non-randomised studies Single-arm studies	Systematic reviews, meta-analysis, conference papers, book chapters or studies published in languages other than English.

ACL anterior cruciate ligament, H/Q hamstrings to quadriceps.