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. 2021 Dec 14;14(12):1303. doi: 10.3390/ph14121303
AP action potentials
APD AP duration
ARDA Atrial selective therapeutic agents
ChTx Charybdotoxin
CMs cardiomyocytes
EADs probability of early afterdepolarizations
ERG ether-á-go-go gene
ERP effective refractory period
GOF gain of function
hiAM human immortalized atrial myocyte
iAM immortalized atrial myocyte
IK,ACh acetylcholine-sensitive inward rectifier potassium current
IKr rapidly activating
IKs slowly activating
IKur ultra-rapidly activating
IL Interleukin
Ito1 the “transient outward” potassium current
Kv voltage-gated potassium channels
KTx potassium channel toxins
LOF loss of function
MgTx Margatoxin
PAH pulmonary arterial hypertension
ProTx2 Protoxin II
SPPS solid-phase peptide synthesis
SR sinus rhythm
TTX tetrodotoxin
VGICs Voltage-gated ion channels
Vmax maximum speed of depolarization
VSD voltage-sensing domain
VSP voltage-sensing phosphatase