Table 1.

Impact of phytotherapy on ejaculatory status.

Reference	Aim	Study Design	Main Results	EjD Results
MacDonald R, et al., BJU Int. June 2012 [18]	To estimate the effectiveness and harms of Serenoa repens monotherapy in the treatment of lower urinary tract symptoms (LUTS) consistent with benign prostatic hyperplasia	Systematic review 17 randomised study, phytotherapy vs. placebo	Serenoa repens therapy does not improve LUTS or Q (max) compared with placebo	Not studied
Bauer HW et al., MMW Fortschr Med. 24 June 1999 [17]	To evaluate the efficacy of Saw palmetto fruit on urinary function	placebo-controlled double-blind study. Moderate-term study (6 months)	Statistically significant improvement of IPSS with Serenoa repens therapy (37% improvement) vs. placebo (14%)	No ejaculatory changes under phytotherapy
Debruyne et al., Eur Urol. May 2002 [19]	To assess the equivalent efficacy of Permixon and tamsulosin.	Prospective, double-blind randomized trial	no differences were observed in either irritative or obstructive symptom improvements after 1-year follow-up	ejaculation disorders occurred more frequently in the tamsulosin group (4.2% vs. 0.6% in Permixon group p = 0.001).