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. 2021 Dec 13;13(12):4455. doi: 10.3390/nu13124455

Figure 1.

Figure 1

Screening of small molecules repressing luciferase activity of TOPFlash and NF-κB response element system. (A,B). Luciferase activities of TOPFlash (A) and NF-κB response element (B) reporter system upon small molecule library treatment. The fold changes of sesamin-regulated luciferase activity were highlighted. (C). Two-dimensional diagram with both luciferase reporter activities were plotted and sesamin was highlighted. (D,E). Luciferase activity of TOPFlash (D) and NF-κB response element (E) reporter system were decreased upon treatment with sesamin at different concentrations (n = 6; * p < 0.05, ** p < 0.01, *** p < 0.001).