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. 2021 Nov 27;19(12):677. doi: 10.3390/md19120677

Figure 6.

Figure 6

Effects of compounds 1, 5, 6, or 10 on NO release in macrophage cells. RAW 264.7 macrophage cells were pretreated for 3 h with the selected compound at 10 μM, followed by stimulation with 200 ng/mL LPS for 24 h. Nitrite accumulation in the culture media was measured using the Griess method. Results are expressed as fold change relative to the LPS condition and are mean ± SD (n ≥ 3 independent experiments performed in duplicate). Significant differences were determined by two-way ANOVA followed by Bonferroni t-test; * p ≤ 0.05 vs. LPS; # p ≤ 0.05 vs. Basal.