Table 1.
NMR data of rugukadiol A (1) in CD3OD a,b.
| Position | δC, Type | δH, m (J in Hz) | Position | δC, Type | δH, m (J in Hz) |
|---|---|---|---|---|---|
| 1 | 42.7, CH | 2.53, m | 11 | 13.4, CH3 | 0.92, d (7.0) |
| 2 | 82.2, CH | 4.66, ddd (8.6, 8.0, 7.5) | 12 | 39.8, CH2 | 1.93, dd (12.1, 2.0) 1.49, ddd (12.1, 5.8, 1.9) |
| 3 | 43.6, CH2 | 2.91, dd (14.5, 7.5) 1.57, dd (14.5, 8.0) |
13 | 138.3, C | |
| 4 | 82.1, C | 14 | 22.4, CH3 | 1.70, d (1.2) | |
| 5 | 76.3, CH | 5.23, ddd (4.0, 1.9, 1.9) | 15 | 127.2, CH | 5.18, br t (7.4) |
| 6 | 30.6, CH2 | 2.37, ddd (14.8, 13.4, 4.0) 1.58, m |
16 | 27.7, CH2 | 2.68, m |
| 7 | 40.1, CH | 2.88, dd (13.4, 4.8) | 17 | 124.2, CH | 5.06, br t (7.2) |
| 8 | 38.3, CH | 1.97, br d (5.5) | 18 | 132.0, C | |
| 9 | 53.1, CH | 2.41, br d (8.5) | 19 | 25.9, CH3 | 1.67, d (1.1) |
| 10 | 89.3, C | 20 | 17.9, CH3 | 1.64, br s | |
| CH3COO (2) | 172.9, C | ||||
| CH3COO (2) | 21.0, CH3 | 2.03, s | |||
| CH3COO (5) | 172.8, C | ||||
| CH3COO (5) | 21.5, CH3 | 2.09, s |
a 1H at 500 MHz, 13C at 125 MHz; b assignments aided by COSY, HSQC, HMBC, and NOESY experiments.