Table 1.
Mode of action of phytochemicals with known inhibitory activity against enteric pathogens that caused foodborne illness from contaminated produce.
Class | Bioactive Compound | Mode of Action | Antimicrobial Activity Against | Reference |
---|---|---|---|---|
Flavonoids | Quercetin | Disruption of cell membrane integrity leading to cell leakage. Enzyme inhibition |
E. coli
S. aureus |
[106,107,108] |
Epigallocatechin-3-gallate | Damage to lipid bilayer |
E. coli
S. aureus |
[109] | |
Luteolin | Membrane alteration and protein inhibition | E. coli | [110] | |
Tannins | Gallotannins Ellagitannins |
Enzyme inhibition, substrate deprivation, metabolism reduction, and Fe deprivation |
S. enterica
E. coli L. monocytogenes |
[111,112] |
Phenylpropanoids | Coumaric acid Caffeic acid Ferulic acid |
Acidification of cytoplasm, physiological disturbances due to accumulation of weak acid anion |
L. monocytogenes
E. coli B. Subtilis Lactobacillus spp. |
[113,114,115] |