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. 2021 Dec 16;13(12):2169. doi: 10.3390/pharmaceutics13122169

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Examine the depression-like behavior in the mTBI-J rats. (A) The preference ratio of the mTBI-J group in the sucrose preference test was decreased compared with the sham group (two-way ANOVA, p = 0.0079). (B) The average preference ratio was summarized, and a significant difference was found among the mTBI-J and sham control groups. (C) The immobility percentage in the forced swimming test was significantly increased in the mTBI-J animals. Data was presented as a mean ± SEM (* = p < 0.05, ** = p < 0.01).