Table 4.
Sensitivity and specificity of individual macrovascular assessment in relation to monophasic arterial flow supplying the relevant angiosome.
| Evaluated parametersDetermined values | SBP DPA – sensitivity (95% CI) | SBP DPA – specificity (95% CI) | Evaluated parameter | SBP PTA – sensitivity (95% CI) | SBP PTA – specificity (95% CI) | Evaluated parameter | SBP TP – sensitivity (95% CI) | SBP TP – specificity (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|
| <20 mm Hg | 0.0% (0.0-8.8) | 100% (90.0-100) | <0 mm Hg | 0% (0-6.7) | 100% (91.0-100) | <15 mm Hg | 0% (0-9.0) | 100% (90.3-100) | |
| ≤75 | 7.5% (1.6-20.4) | 100% (90.0-100) | ≤20 | 9.43% (3.1-20.7) | 100% (91.0-100) | ≤20 | 2.56% (0.06-13.5) | 97.22% (85.5-99.9) | |
| ≤80 | 10% (2.8-23.7) | 97.14% (85.1-99.9) | ≤70 | 11.32% (4.3-23.0) | 97.44% (86.5-99.9) | ≤30 | 10.26% (2.9-24.2) | 97.22% (85.5-99.9) | |
| ≤100 | 27.5% (14.6-43.9) | 97.14% (85.1-99.9) | ≤90 | 20.75% (10.8-34.1) | 97.44% (86.5-99.9) | ≤40 | 12.82% (4.3-27.4) | 88.89% (73.9-96.9) | |
| ≤110 | 27.5% (14.6-43.9) | 94.29% (80.8-99.3) | ≤100 | 24.53% (13.8-38.3) | 89.74% (75.8-97.1) | ≤47 | 25.64% (13-42.1) | 88.89% (73.9-96.9) | |
| ≤116 | 32.5% (18.6-49.1) | 94.29% (80.8-99.3) | ≤104 | 28.3% (16.8-42.3) | 89.74% (75.8-97.1) | ≤50 | 33.33% (19.1-50.2) | 83.33% (67.2-93.6) | |
| ≤120 | 35% (20.6-51.7) | 88.57% (73.3-96.8) | ≤116 | 41.51% (28.1-55.9) | 82.05% (66.5-92.5) | ≤55 | 46.15% (30.1-62.8) | 83.33% (67.2-93.6) | |
| ≤130 | 47.5% (31.5-63.9) | 88.57% (73.3-96.8) | ≤130 | 56.6% (42.3-70.2) | 74.36% (57.9-87.0) | ≤60 | 69.23% (52.4-83) | 77.78% (60.8-89.9) | |
| ≤140 | 55% (38.5-70.7) | 80% (63.1-91.6) | ≤140 | 56.6% (42.3-70.2) | 71.79% (55.1-85.0) | ≤64 | 69.23% (52.4-83) | 75% (57.8-87.9) | |
| ≤142 | 57.5% (40.9-73.0) | 80% (63.1-91.6) | ≤142 | 58.49% (44.1-71.9) | 71.79% (55.1-85.0) | ≤70 | 74.36% (57.9-87.0) | 63.89% (46.2-79.2) | |
| ≤150 | 62.5% (45.8-77.3) | 74.29% (56.7-87.5) | ≤150 | 62.26% (47.9-75.2) | 69.23% (52.4-83.0) | ≤75 | 76.92% (60.7-88.9) | 63.89% (46.2-79.2) | |
| ≤156 | 65% (48.3-79.4) | 74.29% (56.7-87.5) | ≤160 | 64.15% (49.8-76.9) | 69.23% (52.4-83.0) | ≤80 | 87.18% (72.6-95.7) | 55.56% (38.1-72.1) | |
| ≤160 | 70% (53.5-83.4) | 71.43% (53.7-85.4) | ≤170 | 69.81% (55.7-81.7) | 64.1% (47.2-78.8) | ≤85 | 92.31% (79.1-98.4) | 52.78% (35.5-69.6) | |
| ≤180 | 70% (53.5-83.4) | 54.29% (36.6-71.2) | ≤180 | 73.58% (59.7-84.7) | 43.59% (27.8-60.4) | ≤90 | 94.87% (82.7-99.4) | 33.33% (18.6-51) | |
| ≤190 | 75% (58.8-87.3) | 48.57% (31.4-66) | ≤190 | 75.47% (61.7-86.2) | 38.46% (23.4-55.4) | ≤100 | 97.44% (86.5-99.9) | 22.22% (10.1-39.2) | |
| ≤200 | 75% (58.8-87.3) | 37.14% (21.5-55.1) | ≤200 | 77.36% (63.8-87.7) | 35.9% (21.2-52.8) | ≤110 | 100% (91-100) | 19.44% (8.2-36) | |
| ≤220 | 85% (70.2-94.3) | 11.43% (3.2-26.7) | ≤220 | 92.45% (81.8-97.9) | 15.38% (5.9-30.5) | ≤170 | 100% (91-100) | 0% (0-9.7) | |
| Significance p=0.0032 | Youden’s J index 0.414 | Significance p=0.0032 | Youden’s J index 0.3391 | Significance p<0.0001 | Youden’s J index 0.4701 | ||||
| AUC 0.687 | 95% confidence interval 0.569 to 0.789 | AUC 0.667 | 95% confidence interval 0.561 to 0.762 | AUC 0.762 | 95% confidence Interval 0.649 to 0.853 | ||||
|
Evaluated parameters
Determined values |
ABI DPA – sensitivity (95% CI) | ABI DPA – specificity (95% CI) | Evaluated parameter | ABI PTA– sensitivity (95% CI) | ABI PTA– specificity (95% CI) | Evaluated parameter | TBI – sensitivity (95% CI) | TBI – Specificity (95% CI) | |
| <0.18 | 0.0% (0.0-9.5) | 100% (92-100) | <0 | 0.0% (0.0-7.3) | 100% (92.6-100) | <0.13 | 0.0% (0.0-8.8) | 100% (90.3-100) | |
| ≤0.58 | 8.11% (1.7-21.9) | 100% (92-100) | ≤0.47 | 10.2% (3.4-22.2) | 100% (92.6-100) | ≤0.23 | 10% (2.8-23.7) | 97.2% (85.5-99.9) | |
| ≤0.62 | 8.11% (1.7-21.9) | 97.73% (88-99.9) | ≤0.54 | 12.24% (4.6-24.8) | 97.92% (88.9-99.9) | ≤0.31 | 30% (16.6-46.5) | 91.67% (77.5-98.2) | |
| ≤0.82 | 35.14% (20.2-52.5) | 97.73% (88-99.9) | ≤0.62 | 16.33% (7.3-29.7) | 95.83% (85.7-99.5) | ≤0.34 | 40% (24.9-56.7) | 86.11% (70.5-95.3) | |
| ≤0.83 | 37.84% (22.5-55.2) | 93.18% (81.3-98.6) | ≤0.7 | 28.57% (16.6-43.3) | 89.58% (77.3-96.5) | ≤0.4 | 52.5% (36.1-68.5) | 77.78% (60.8-89.9) | |
| ≤0.9 | 40.54% (24.8-57.9) | 90.91% (78.3-97.5) | ≤0.8 | 42.86% (28.8-57.8) | 77.08% (62.7-88) | ≤0.43 | 72.5% (56.1-85.4) | 75% (57.8-87.9) | |
| ≤0.933 | 48.65% (31.9-65.6) | 90.91% (78.3-97.5) | ≤0.9 | 55.1% (40.2-69.3) | 70.83% (55.9-83) | ≤0.47 | 77.5% (61.5-89.2) | 75% (57.8-87.9) | |
| ≤0.96 | 48.65% (31.9-65.6) | 86.36% (72.6-94.8) | ≤1.01 | 69.39% (54.6-81.7) | 68.75% (53.7-81.3) | ≤0.5 | 85% (70.2-94.3) | 58.33% (40.8-74.5) | |
| ≤1 | 75.68% (58.8-88.2) | 68.18% (52.4-81.4) | ≤1.06 | 73.47% (58.9-85.1) | 62.5% (47.4-76) | ≤0.53 | 92.5% (79.6-98.4) | 55.56% (38.1-72.1) | |
| ≤1.05 | 78.38% (61.8-90.2) | 63.64% (47.8-77.6) | ≤1.17 | 75.51% (61.1-86.7) | 47.92% (33.3-62.8) | ≤0.57 | 95% (83.1-99.4) | 52.78% (35.5-69.6) | |
| ≤1.1 | 78.38% (61.8-90.2) | 56.82% (41-71.7) | ≤1.22 | 81.63% (68-91.2) | 45.83% (31.4-60.8) | ≤0.6 | 97.5% (86.8-99.9) | 47.22% (30.4-64.5) | |
| ≤1.16 | 83.78% (68-93.8) | 52.27% (36.7-67.5) | ≤1.26 | 85.71% (72.8-94.1) | 41.67% (27.6-56.8) | ≤1.13 | 100% (91.2-100) | 0% (0-9.7) | |
| ≤1.3 | 86.49% (71.2-95.5) | 31.82% (18.6-47.6) | ≤1.4 | 85.71% (72.8-94.1) | 20.83% (10.5-35) | ||||
| ≤1.38 | 89.19% (74.6-97) | 22.73% (11.5-37.8) | ≤1.52 | 93.88% (83.1-98.7) | 8.33% (2.3-20) | ||||
| ≤1.52 | 97.3% (85.8-99.9) | 6.82% (1.4-18.7) | |||||||
| Significance p<0.0001 | Youden’s J index 0.4386 | Significance p=0.0009 | Youden’s J index 0.3814 | Significance p<0.0001 | Youden’s J index 0.5250 | ||||
| AUC 0.768 | 95% confidence interval 0.660 to 0.854 | AUC 0.683 | 95% confidence interval 0.581 to 0.774 | AUC 0.798 | 95% confidence interval 0.690 to 0.881 | ||||
SBP, systolic blood pressure; DPA, dorsalis pedis artery; PTA, posterior tibial artery; TP, toe pressure; p, significance; CI, confidence interval, mm Hg, millimetres of mercury; AUC, area under the ROC curve; ABI, ankle-brachial index; TBI, toe-brachial index; p, significance; the highest sensitivity and specificity for individual measurements are highlighted in bold.