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. 2021 Dec 16;26(24):7646. doi: 10.3390/molecules26247646

Table 18.

Chromone alkaloids aminoglycosides with their sources and biological activities.

No. Compound Source Biological Activity
168 Kidamycin (rubiflavin B) Streptomyces phaeoverticillatus var.
takatsukiensis [138]
Antibiotic with MIC (minimum inhibitory concentration) ranges from 0.19–1.56 μg/mL and potent antitumor activity [138]
169 Neopluramycin Streptomyces pluricolorescens [139,140] Antibiotics and potent antitumor activity [140]
170 14, 16-Epoxykidamycin Streptomyces pluricolorescens [141] Antibiotic against Gram-positive bacteria with MIC ranges from 0.5 to 10 μg/mL and antitumor activity [141]
171 Pluramycin A Streptomyces pluricolorescens [139,140] Antibiotic and antitumor activity [140]
172 Rubiflavin A Streptomyces species [142] Antibiotic and antitumor activity [142]
173 Rubiflavin C-1
174 Rubiflavin C-2
175 Rubiflavin D
176 Rubiflavin E
177 Rubiflavin F (isokidamycin)
178 PD 121,222 Streptomyces species [143] Antibiotic and potent antitumor activity [143]
179 Hedamycin Streptomyces griseoruber [144,145] Antibiotic and potent antitumor activity against HeLa cells [144]
180 Ankinomycin (deangolosaminylhedamycin) Streptomyces species [146] Antibiotic against Gram-positive bacteria with MICs ranges from 0.39–1.56 μg/mL and potent antitumor activity [146]
181 Pluraflavin A Saccharothrix species [147] Antibiotic and potent antitumor activity [147]
182 Pluraflavin B
183 Pluraflavin E
184 Altromycin A Actinomycete, AB 1246E-26 [148,149] Antibiotic against Gram-positive bacteria and potent antitumor activity [137]
185 Altromycin B
186 Altromycin C
187 Altromycin D
188 Altromycin E Actinomycete, AB 1246E-26 [137]
189 Altromycin F
190 Altromycin G
191 Altromycin H
192 Altromycin I