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Inhibitory effects of SF5-SAHA on EGFR signaling pathway protein expression. (A) Representative Western blots of n = 3 independent experiments showing treatment induced changes in the expression of EGFR in DU145 cells after 24 h. β-actin was used as loading control. (B) From these Western blots gray intensity, mean ± SEM, of EGFRs specific bands were quantified and adjusted to protein loading and normalized to untreated control. ** p ≤ 0.005; 2-way ANOVA Dunnett’s post-hoc test.
