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. 2021 Dec 3;13(12):4359. doi: 10.3390/nu13124359

Table 4.

Articles included in the systematic review that investigated the effect of l-Carnitine on low–moderate-intensity (50–79% V˙O2 max) athletic performance variables.

Author/s Population Intervention Outcomes Analyzed Main Results
Chronic l-C supplementation
Broad et al., 2005 [30] 15 endurance-trained men (20 to 46 years) 3 g of l-CLT (2 g l-C)
Duration: 4 weeks and 2 weeks washout period between them
90 min at 65% V˙O2 max on cycle ergometer:
  • Borg scale

  • V˙O2

20 km time trial duration:
Total time trial
  • Total time trial

Smith et al., 2008 [34] 32 untrained participants (9 men and 23 women (18 to 44 years) 1 g/day of PL-C n = 11
3 g/day of PL-C n= 12
Duration: 8 weeks
Aerobic exercise test on the treadmill: GPL-C-1 GPL-C-3
  • Borg scale

  • V˙O2 peak

  • Total exercise time

Wall et al., 2011 [23] 14 Moderately trained recreational athletes (25.9 ± 2.1 years) 4 g of l-CLT (2,72 l-C) with 160 g of CHO distributed 2 times per day (1 at breakfast and 4 h later
Duration: 24 weeks
Test on cycle ergometer at 50% V˙O2 max: week 12 week 24
  • Borg scale

Acute l-C supplementation
Colombani et al., 1996 [20] 7 endurance-trained men (36 ± 3 years) 2 g of l-C 2 h before the marathon and 2 g of l-C after 20 km
125 mL of sugar tea every 5 km and 500 mL during the next hour after the marathon
Marathon:
  • Total time

Burrus et al., 2018 [24] 10 moderately active men (27 ± 4 years) 3 g of l-C + 200 mL of H2O
3 h before the exercise
94 g of CHO in 500 mL of H2O
2 h before the exercise
94 g of CHO in 500 mL of H2O
30 min before the exercise
Test on cycle ergometer at 65% V˙O2 peak:
  • Power at 0, 10, 20, 30 y 40 min

Legend: ↔ no difference in effects between groups (p > 0.05); CHO: carbohydrates; l-CLT: L-Carnitine l-tartrate; l-C: l-carnitine; PL-C: propionyl l-carnitine.