Skip to main content
. 2021 Dec 9;22(24):13262. doi: 10.3390/ijms222413262

Table 3.

Poisonous activity of insecticidal triterpenoids of plants from 8 genera in Meliaceae.

Compound Plant Source Insect Activity Ref.
Aphapolynin D Aphanamixis polystachya Diabrotica balteata MS: 66 5–9 d) [19]
Aphanalide F Aphanamixis polystachya Diabrotica balteata MS: 66 (5–9 d)
Aphapolynin F Aphanamixis polystachya Diabrotica balteata MS: 33 (5–9 d)
Dregenana-1 Aphanamixis polystachya Diabrotica balteata MS: 33 (5–9 d)
Aphanalide E Aphanamixis polystachya Diabrotica balteata MS: 33 (5–9 d)
Aphanalide G Aphanamixis polystachya Diabrotica balteata MS: 33 (5–9 d)
Aphanalide H Aphanamixis polystachya Diabrotica balteata MS: 99 (5–9 d)
Aphapolynin C Aphanamixis polystachya Diabrotica balteata MS: 99 (5–9 d)
Aphanamixis polystachya Caenorhabditis elegans MS: 66 (5–9 d)
Aphapolynin A Aphanamixis polystachya Plutella xylostella MS: 66 (5–9 d)
Zaphaprinin I Aphanamixis polystachya Plutella xylostella MS: 99 (5–9 d)
Zaphaprinin R Aphanamixis polystachya Plutella xylostella MS: 99 (5–9 d)
Azadirachtin Azadirachta indica Azadirachta excelsa Spodoptera littoralis LC50 = 0.32 μg/mL (12 d) [9,10,11,12,13,15,16,33,35,36]
Anopheles gambiae LD50 = 57.1 μg/mL (24 h)
Plutella xylostella LD50 = 7.04–0.87 (24–96 h)
7-deacetylgedunin Azadirachta indica Atta sexdens rubropilosa S50 = 9 d at 100 μg/mL [28]
Cedrela fissilis
Cedrela sinensis
Gedunin Azadirachta indica Spodoptera frugiperda LC50 = 39 μg/mL (7 d) [43]
Cedrela dugessi
Cedrela fissilis
Cedrela sinensis
Cedrela salvadorensis
Cabralea eichleriana
Carapa guianensis
Chisocheton paniculatus
Nimocinol Azadirachta indica Aedes aegypti LC50 = 21 μg/mL (24 h) [25]
6α-O-acetyl-7-deacetyl-
nimocinol
Azadirachta indica Aedes aegypti LC50 = 83 μg/mL (24 h) [25]
22,23-dihydronimocinol Azadirachta indica Anopheles stephensi LC50 = 60 μg/mL (24 h) [26]
desfurano-6α-hydroxy-
azadiradione
Azadirachta indica Anopheles stephensi LC50 = 43 μg/mL (24 h) [26]
Meliatetraolenone Azadirachta indica Anopheles stephensi LC50 = 16 μg/mL (24 h) [26]
Odoratone Azadirachta indica Anopheles stephensi LC50 = 154 μg/mL (24 h) [44]
Azadirachtin O Azadirachta excelsa Plutella xylostella LD50 = 3.92 μg/g (24 h) [33]
Azadirachtin P Azadirachta excelsa Plutella xylostella LD50 = 2.19 μg/g (24 h) [33]
Azadirachtin Q Azadirachta excelsa Plutella xylostella LD50 = 1.10 μg/g (96 h) [33]
Azadirachtin B Azadirachta excelsa Plutella xylostella LD50 = 1.06 μg/g (96 h) [33]
Azadirachtin L Azadirachta excelsa Plutella xylostella LD50 = 1.92 μg/g (96 h) [33]
Azadirachtin M Azadirachta excelsa Plutella xylostella LD50 = 1.30 μg/g (96 h) [33]
11α-azadirachtin H Azadirachta excelsa Plutella xylostella LD50 = 0.75 μg/g (96 h) [33]
Azadirachtol Azadirachta excelsa Plutella xylostella LD50 = 1.78 μg/g (96 h) [33]
23-O-methylnimocinolide Azadirachta indica Aedes aegypti LC50 = 53 μg/mL (24 h) [45]
7-O-deacetyl-23-O-methyl-
7α-O-senecioyl-nimocinolide
Azadirachta indica Aedes aegypti LC50 = 14 μg/mL (24 h) [45]
6α-acetoxygedunin Aglaia elaeagnoidea Atta sexdens rubropilosa S50 = 8 d at 100 μg/mL [28]
Carapa guianensis
Cedrela fissilis
Chisocheton paniculatus
14-deoxy-Δ14,15-xyloccensin K Chisocheton erythrocarpus Hiern Aedes aegypti,
Aedes albopictus
Culex Quinquefasciatus
LC50 = 10.2 μg/mL (24 h) LC50 = 12.16 μg/mL (24 h) LC50 = 16.82 μg/mL (24 h) [46]
14-deoxyxyloccensin K Chisocheton erythrocarpus Hiern
Chisocheton ceramicus
Aedes aegypti,
Aedes albopictus
Culex Quinquefasciatus
LC50 = 3.19 μg/mL (24 h)
LC50 = 3.01 μg/mL (24 h) LC50 = 3.64 μg/mL (24 h)
[46]
Photogedunin epimer mixture Cedrela dugessi Spodoptera frugiperda LC50 = 10 μg/mL (7 d) [47]
Photoacetic acid acetate mixture Cedrela dugessi Spodoptera frugiperda LC50 = 8 μg/mL (7 d) [47]
7-deacetoxy-7-oxo-gedunin Cedrela fissilis Atta sexdens rubropilosa S50 = 11 d at 100 μg/mL [28]
Cabralea eichleriana
Carapa guianensis
Photogedunin Cedrela fissilis Atta sexdens rubropilosa S50 = 9 d at 100 μg/mL [28]
1,2-dihydro-3β-hydroxy-7-
deacetoxy-7-oxogedunin
Cedrela fissilis Atta sexdens rubropilosa S50 = 9 d at 100 μg/mL
Cipadesin B Cedrela fissilis Atta sexdens rubropilosa S50 = 9 d at 100 μg/mL [28]
Swietemahonolide Cedrela fissilis Atta sexdens rubropilosa S50 = 8 d at 100 μg/mL
3β-acetoxycarapin Cedrela fissilis Atta sexdens rubropilosa S50 = 8 d at 100 μg/mL
Oleanolic acid Cedrela fissilis Atta sexdens rubropilosa S50 = 6 d at 100 μg/mL
Oleanonic acid Cedrela fissilis Atta sexdens rubropilosa S50 = 8 d at 100 μg/mL
Methyl angolensate Cedrela fissilis Spodoptera frugiperda MR: 40% at 50 mg/kg (7 d) [48]
Cabralea canjerana
Photogeduninepimeric acetate mixture Cedrela salvadorensis Spodoptera frugiperda SR 50% at 10 μg/mL (24 h) [49]
Photogeduninepimeric mixture Cedrela salvadorensis Spodoptera frugiperda SR 17% at 10 μg/mL (24 h)
Ocotillone Cabralea canjerana Spodoptera frugiperda MR: 40% at 50 mg/kg (7 d) [48]
β-photogedunin Carapa guianensis Spodoptera frugiperda LM 53.3% at 50 μg/mL (7 d) [48]
PM 20.0% at 50 μg/mL (7 d)

MS: mortality scored; SR: survival rate; MR: mortality rate; LM: larval mortality; PM: pupal mortality.