. 2021 Dec 9;22(24):13262. doi: 10.3390/ijms222413262

Table 4.

Growth regulatory activity of insecticidal triterpenoids of plants from 8 genera in Meliaceae.

Compound	Plant Source	Insect	Activity	Ref.
Azadirachtin	Azadirachta indica Azadirachta excelsa	Helicoverpa armigera	IGR, EC₅₀ = 0.26 μg/mL (7 d)	[9,10,11,12,13,15,16,33,35,36]
		Rhodnius prolixus	IGR, ED₅₀ = 0.40 μg/mL (7 d)
		Heliothis zea Heliothis virescens	IGR, ED₅₀ = 0.70 μg/mL (10 d)
		Spodoptera frugiperda, Pectinophora gossypiella	IGR, ED₅₀ = 0.40 μg/mL (10 d)
		Spodoptera litura	IGR, EC₅₀ = 0.21 μg/mL (7 d)
		Spodoptera littoralis	EC₅₀ = 0.11 μg/mL (6 d)
Nimocinolide	Azadirachta indica	Musca domestica	FI at 100 μg/mL	[27]
Isonimocinolide	Azadirachta indica	Musca domestica	FI at 100 μg/mL	[27]
Isonimocinolide	Azadirachta indica	Aedes uegypti	mutagenic properties	[27]
7-deacetylazadiradione	Azadirachta indica	Heliothis virescens	IGR, EC₅₀ = 1600 μg/mL	[30]
7-deacetylazadiradione	Chisocheton paniculatus	Heliothis virescens	IGR, EC₅₀ = 1600 μg/mL	[30]
Salannin	Azadirachta indica	Helicoverpa armigera	IGR EC₅₀ = 86.5 μg/mL (7 d)	[22]
Salannin	Azadirachta indica	Spodoptera litura	IGR EC₅₀ = 87.7 μg/mL (7 d)	[22]
3-O-acetyl salannol	Azadirachta indica	Helicoverpa armigera	IGR EC₅₀ = 64.2 μg/mL (7 d)	[22]
3-O-acetyl salannol	Azadirachta indica	Spodoptera litura	IGR EC₅₀ = 65.6 μg/mL; RF₅₀ at 2.0 µg/cm² (7 d)	[22]
Salannol	Azadirachta indica	Helicoverpa armigera	IGR, EC₅₀ was 79.7 μg/mL (7 d)	[22]
Salannol	Azadirachta indica	Spodoptera litura	IGR, EC₅₀ = 77.4 μg/mL (7 d)	[22]
6β-hydroxygedunin	Azadirachta indica	Helicoverpa armigera	IGR EC₅₀ = 24.2 μg/mL (7 d)	[35]
	Azadirachta indica	Spodoptera litura	IGR EC₅₀= 391.4 μg/mL (7 d)	[35]
Nimbinene	Azadirachta indica	Helicoverpa armigera	IGR EC₅₀ was 21.5 μg/mL (7 d)	[35]
Nimbinene	Azadirachta indica	Spodoptera litura	IGR EC₅₀ = 404.5 μg/mL (7 d)	[35]
Azadiradione	Azadirachta indica	Heliothis virescens	IGR, EC₅₀= 560 μg/mL	[30]
	Chisocheton siamensis	Heliothis virescens	IGR, EC₅₀= 560 μg/mL	[30]
	Azadirachta indica	Heliothis virescens	IGR, EC₅₀ = 560 μg/mL	[30]
	Chisocheton siamensis	Heliothis virescens	IGR, EC₅₀ = 560 μg/mL	[30]
6α-acetoxygedunin	Aglaia elaeagnoidea	Ostrinia nubilalis	reduced growth at 50 μg/mL	[17]
	Carapa guianensis
	Cedrela fissilis
	Chisocheton paniculatus
Cedrelanolide I	Cedrela salvadorensis	Ostrinia nubilalis	reduced weight at 50 μg/mL	[51]
Cedrelone	Cedrela odorata	Peridroma saucia	IGR, EC₅₀ = 53.1 μg/mL (9 d)	[29]
Cedrelone	Cedrela toona	Peridroma saucia	IGR, EC₅₀ = 53.1 μg/mL (9 d)	[29]
Cabraleadiol	Cabralea canjerana	Spodoptera frugiperda	LPE, 1.2 d	[48]
3β-deacetylfissinolide	Cabralea canjerana	Spodoptera frugiperda	LPE, 1.2 d	[48]
β-photogedunin	Carapa guianensis	Spodoptera frugiperda	PWI at 50 mg/kg (7 d)	[48]
Cedrelanolide I	Cedrela salvadorensis	Ostrinia nubilalis	reduced weight at 50 μg/mL	[51]
Meliantriol	Azadirachta indica	Locusts	chewing prevention	[52]
7-deacetyl-17β-hydroxy-azadiradione	Azadirachta indica	Heliothis virescens	IGR, EC₅₀ = 240 μg/mL	[30]

IGR: insect growth inhibitory activity; LPE: larval phase extended; FI: fecundity inhibition; RF₅₀: reduced feeding by 50%; PWI: pupal weight inhibition.