Table 1.

Antibacterial effect of semisynthetic pleuromutilins based on Minimal Inhibitory Concentration [28] of active compounds (MIC: mg/L) (ATCC: American Type Culture Collection, MRSA/MSSA: methicillin resistant/sensitive S. aureus, VanA and VanB: vancomycin resistant phenotypes.)

Bacterial Strains	1	10j	10k	11h	3	14j	14k	15h
Bacillus subtilis ATCC 6633	16	32	4	32	0.5	16	256	512
Staphylococcus aureus MSSA ATCC 29213	4	16	8	16	0.5	16	512	512
Staphylococcus aureus MRSA ATCC 33591	2	4	4	4	0.5	32	512	256
Staphylococcus epidermidis ATCC 35984 biofilm	1	2	0.5	2	0.5	16	512	128
Staphylococcus epidermidis mecA	4	16	8	16	0.5	16	512	256
Enterococcus faecalis ATCC 29212	64	256	32	256	64	64	512	512
Enterococcus faecalis 15376 VanA	128	256	64	128	1	16	512	256
Enterococcus faecium VanA 38276 urine	128	128	128	128	1	2	256	256
Enterococcus faecium VanA 25192 bloodculture	128	128	128	128	2	2	512	256
Enterococcus faecium VanA 3452 drain	2	2	2	2	1	2	256	512
Enterococcus faecium VanA 24581 wound	128	128	128	128	1	1	512	512
Enterococcus faecalis ATCC 51299 VanB	128	256	32	256	64	64	256	256