Table 2.
Peak times of CWA-APTT and sTF/FIXa in healthy volunteers and patients with platelet counts of ≥8.0 × 104/L or <8.0 × 104/L.
| 2nd DP | 1st DP | FF | 2nd DP | 1st DP | FF | |
|---|---|---|---|---|---|---|
| Healthy volunteers | 31.7 (31.1–32.9) |
34.3 (33.8–36.0) |
36.0 (35.6–38.2) |
77.5 (70.3–85.9) |
96.5 (89.3–108) |
95.4 (89.5–108) |
| platelet counts | CWA-APTT | CWA-sTF/FIXa | ||||
| ≥8.0 × 104/L | 33.6 (30.7–38.5) |
36.4 (33.0–40.5) |
38.2 (35.2–45.9) |
79.0 (74.3–88.8) |
100 (90.5–113) |
104 (94.1–117) |
| <8.0 × 104/L | 33.9 * (30.9–37.9) |
37. 2 * (33.8–42.0) |
39.3 ** (35.9–44.1) |
73.6 *** (65.3–82.6) |
90.4 *### (81.5–102) |
90.9 ### (82.9–104) |
Data are expressed as median (25th–75th percentile); CWA, clot waveform analysis; APTT, activated partial thromboplastin time; sTF/FIXa, small amount of tissue factor-induced FIX activation assay; 2nd DP, second derivative peak; 1st DP, first derivative peak; FF, fibrin formation; *, p < 0.05; **, p < 0.01; ***, p < 0.001 in comparison to healthy volunteers; ###, p < 0.001 in comparison with patients with platelet counts of <8.0 × 104/L.