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. 2021 Dec 24;45(4):675–685. doi: 10.1038/s41440-021-00832-w

Table 1.

Clinical background of cases during the state of emergency due to COVID-19.

Total (n = 748) Analyzed cases During the state of emergency
Male (%) 748 424 (57%)
Age (years-old) 748

67.3 ± 12.3

(range, 22–97)

Current smoke 520 31 (6%)
Hypertensin 748 714 (95%)
Diabetes mellitus 748 423 (57%)
Dyslipidemia 610 544 (89%)
Chronic kidney disease 610 336 (55%)
Cardiovascular disease 610 104 (17%)
Cerebrovascular disease 610 40 (7%)
BMI 519 24.0 ± 3.5
BW (kg) 715 63.9 ± 12.8
Office SBP/DBP (mmHg) 748

138.6 ± 18.6/

79.0 ± 12.2

Office MAP (mmHg) 748 99.0 ± 12.5
Pulse rate 520 79.2 ± 13.2
Home SBP/DBP (mmHg) 546

126.8 ± 10.3/

75.3 ± 9.1

Home MAP (mmHg) 546 92.5 ± 8.2
eGFR (mL/min/1.73 m2) 565 66.9 ± 17.8
HbA1c(mmol/mol (%)) 546

48.1 ± 10.1

(6.5 ± 0.9)

Urine albumin-to creatinine ratio (mg/gCr) 391 9.5 [5.4, 26.1]
Urine protein (g/gCr) 79 0.16 [0.05, 0.39]
Estimated Sodium intake (g/day) 503 8.8 [7.2, 10.4]
NT proBNP 178 91.0 [40.5, 193.0]
Current medications were analyzed in 610 cases
 Antihypertensive agents
  ARB 308 (51%)
  ACEI 40 (7%)
  Ca channel blocker 297 (49%)
  β blocker 84 (14%)
  Thiazide 22 (4%)
  Mineralocorticoid receptor blocker 45 (7%)
  Loop diuretic 9 (2%)
hypoglycemic agents
 DPP4 inhibitor 150 (25%)
 Metformin 97 (16%)
 SGLT2 inhibitor 68 (11%)
 Insulin 51 (8%)
 Sulphonyl urea 64 (11%)
 GLP1 receptor agonist 20 (3%)
 Pioglitazone 34 (6%)
 `αGlucosidase inhibitor 70 (12%)
 Glinide 32 (5%)
Others
 Statin 439 (72%)
 Ezetimibe 92 (15%)
 Fibrate 12 (2%)
 Antiplatelet 126 (21%)
 EPA 34 (6%)
 Anticoagulant 22 (4%)

Data shown are mean ± standard deviation, median [lower quartile, upper quartile], or numbers (%).

ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, COVID-19 corona virus disease 2019, BMI body mass index, BW body weight, DBP diastolic blood pressure, DPP4 dipeptidyl peptidase-4, EPA eicosapentaenoic acid, eGFR estimated glomerular filtration rate, GLP1 glucagon-like peptide 1, HbA1c hemoglobin A1c, MAP mean arterial pressure, NT proBNP N-terminal pro-brain natriuretic peptide, SBP systolic blood pressure, SGLT2 sodium-glucose co-transporter 2.