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. 2021 Dec 20;13(12):2553. doi: 10.3390/v13122553

Figure 4.

Figure 4

Humoral immune responses to betacoronaviruses in samples from the heterogeneous prepandemic cohort (n = 70) and samples from COVID-19 ICU patients (n = 86). (a) IgG against the SARS-CoV-2 nucleocapsid; (b) IgG against the SARS-CoV-2 spike RBD; (c) IgG against the SARS-CoV spike protein; (d) IgG against MERS-CoV spike protein; (e) IgG against the OC43 spike protein; (f) IgG against the HKU1 spike protein. The whisker plots show the distribution of IgG antibody titers across the prepandemic and ICU patient samples. The dots show the values of each sample. The solid black line indicates the median, and the top and bottom box boundaries indicate the first and third quartiles.