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. 2021 Nov 29;7(12):1025. doi: 10.3390/jof7121025

Table 4.

Characteristics of C. albicans genes related to virulence and involved in antimicrobial photodynamic therapy.

Candida spp. Photosensitizer Genes Results Origin References
C. albicans
ATCC 18804
Methylene blue SAP5, LIP9 and PLB2 60% SAP5/50% LIP9 and PLB2 Biofilms Freire et al. [62]
C. albicans
ATCC 18804
Methylene blue ALS3, HWP1, BCR1, TEC1, CPH1 y EFG1 ALS3, HWP1, BCR1, TEC1, CPH1 y EFG1 Strains C. albicans from patients with a control strain (ATCC 18804) Freire et al. [63]
C. albicans
ATCC 90028
Photodithazine (PDZ
and
Curcumin
ALS1, HWP1, CAP1, CAT1, SOD1 ALS1, HWP1, CAP1, CAT1,
SOD1
Biofilms Jordão et al. [64]
C. albicans
ATCC 96901
Photodithazine® (PDZ) ALS1, HWP1, EFG1, CAT1, CAP1, SOD1, SAP1, PLB1 and LIP3 Special decrease in SOD1 Colonies from tongues of mice Jordão et al. [65]
C. albicans
ATCC 90028
Photodithazine® (PDZ) plus
Nystatine
ALS1, HWP1, EFG1, CAP1, CAT1, SOD1, SAP1, PLB1 y LIP3 PLB1 y ACT1 Dental patient samples Alonso et al. [66]