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(A) QD-liposomes are able to extravasate through the leaky vessels surrounding the cancer cells (EPR effect) allowing their accumulation at the tumor site. (B) QD-liposomes are then taken up by the cells through their fusion with cellular membranes. (C) Ultrasound can be applied on the tumor site to trigger the release of QDs encapsulated inside the liposome and enhance their uptake by the cancer cells mainly through the sonoporation effect produced by the ultrasound.
