Table 2.
Summary of cancer types 1 with significant correlations (p < 0.001) between the quantity of DNA mutations (global TMB value) and the changes in the copy number (genome-wide HRD scores).
| Positive Correlation | Inverse Correlation |
|---|---|
| OV (R = 0.31) | COAD (R = −0.24) |
| LUSC (R = 0.33) | UCEC (R = −0.32) |
| BLCA (R = 0.38) | |
| PAAD (R = 0.54) | |
| LUAD (R = 0.49) | |
| SARC (R = 0.5) | |
| BRCA (R = 0.54) | |
| THYM (R = 0.32) | |
| KIRC (R = 0.25) | |
| HNSC (R = 0.23) | |
| PRAD (R = 0.39) | |
| LGG (R = 0.34) | |
| PCPG (R = 0.27) | |
| Pan-cancer (R = 0.26) |
1 A full list of TCGA cancer type abbreviations can be found in the Genomic Data Commons (https://gdc.cancer.gov/resources-tcga-users/tcga-code-tables/tcga-study-abbreviations (accessed on 2 June 2021)).