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. 2021 Dec 10;14(12):1292. doi: 10.3390/ph14121292

Table 1.

cLogP and KD values of imidazoquinolines. cLogP was calculated using ChemDraw 19.1 Software—PerkinElmer. KD was estimated (sum of squares) from the membrane vesicle P-gp assay.

Imidazoquinoline cLogP KD (μM)
Imiquimod 1.428 7.66
Resiquimod 0.036 24.37
Gardiquimod −0.254 N.D.