Table 2.

Pre-baseline and on-study annualised bleeding rates of the 6-Month Analysis Population.

	Pre-Baseline n = 225	On-Study n = 224	Total Duration n = 224
Annualised bleed rate, no. of bleeds/year
All bleeds
Mean (SD)	5.34 (10.1)	4.81 (6.83)	5.04 (7.53)
Median (range)	2.00 (0.0, 94.0)	2.05 (0.0, 37.8)	2.61 (0.0, 62.7)
Treated bleeds
Mean (SD)	5.03 (9.35)	4.33 (6.39)	4.64 (7.00)
Median (range)	2.00 (0.0, 86.0)	1.85 (0.0, 37.8)	2.27 (0.0, 57.8)
Treated spontaneous bleeds
Mean (SD)	2.98 (6.02)	1.93 (3.81)	2.35 (4.14)
Median (range)	0.00 (0.0, 58.0)	0.00 (0.0, 25.2)	0.94 (0.0, 39.3)
Treated traumatic bleeds
Mean (SD)	2.05 (6.81)	2.40 (4.58)	2.29 (5.02)
Median (range)	0.00 (0.0, 86.0)	0.00 (0.0, 31.2)	0.88 (0.0, 55.9)
Treated joint bleeds
Mean (SD)	3.74 (7.67)	2.74 (4.68)	3.19 (5.41)
Median (range)	2.00 (0.0, 72.0)	1.21 (0.0, 25.5)	1.44 (0.0, 47.0)
Treated problem joint bleeds
Mean (SD)	1.22 (3.69)	0.66 (2.22)	0.91 (2.63)
Median (range)	0.00 (0.0, 32.0)	0.00 (0.0, 20.0)	0.00 (0.0, 21.4)

SD, standard deviation.