Figure 5.

Blood perfusion recovery of ischemic hindlimb after the treatments for up to 21 days. (A) Representative images of laser Doppler perfusion imaging (LDPI) on day 0, 7, 14 and 21 post-treatments. Blue or dark-blue color indicates low and no perfusion, whereas red or yellow color indicates a high perfusion state. (B) Blood perfusion ratio was evaluated by comparing ischemic limb groups (defect only, PH, and PH/sFDM) with that of normal limb. Statistically significant difference (** p < 0.01, **** p < 0.0001).