Histological sections of kidney, liver and lungs from immunocompetent mice, inoculated with Sporothrix schenckii sensu stricto, S. mexicana, and S. pallida, observed with hematoxylin-eosin preparations 21 days after inoculation. (a,b) S. schenckii sensu stricto. (a) kidney and (b) liver without histological alterations; (c) S.
schenckii sensu stricto, lung. Pneumonia, pyogranulomatous, and mild; (d) S.
mexicana, kidney. Interstitial nephritis, pyogranulomatous, focal, and mild; (e) S.
mexicana, liver. Hepatitis, pyogranulomatous, necrotizing. There are abundant yeasts within macrophages amid the inflammatory infiltrate (circles); (f) S. mexicana, lungs without histological alterations; (g) S. pallida, kidney. Interstitial nephritis, pyogranulomatous, and moderate in the cortex. (h) S. pallida, liver. Hepatitis, granulomatous, focal, and moderate. A well-organized granuloma is observed (arrow); (i) S.
pallida, lung. Pneumonia, granulomatous, multifocal, and moderate. A well-organized granuloma is observed (arrow).