Figure 6.

Histological sections of kidney, liver and lungs from immunocompetent mice, inoculated with Sporothrix schenckii sensu stricto, S. mexicana, and S. pallida, observed with hematoxylin-eosin preparations 35 days after inoculation. (a) S. schenckii sensu stricto, kidney without histological alterations; (b) S. schenckii sensu stricto, liver. Hepatitis, pyogranulomatous, and moderate. Yeasts are observed within macrophages amid the inflammatory infiltrate (circles); (c) S. schenckii sensu stricto, lung. Pneumonia, granulomatous, diffuse, and severe; (d) S. mexicana, kidney. Interstitial nephritis, pyogranulomatous, focal, and discreet in the cortex; (e) S. mexicana, liver. Hepatitis, pyogranulomatous, necrotizing, and moderate. A well-organized granuloma is observed (arrow). (f) S. mexicana, lung. Pneumonia, pyogranulomatous, diffuse, and moderate; (g) S. pallida, kidney without histological alterations; (h) S. pallida, liver. Hepatitis, suppurative infiltrate, multifocal, and mild. (i) S. pallida, lung. Pneumonia, granulomatous, diffuse, and moderate (j) S. mexicana, a nodule in the lower right paw. Panniculitis, pyogranulomatous, diffuse, and severe.