Table 2.
List of significantly downregulated genes in chicken small intestinal mucosa in response to C. perfringens infection.
| Gene ID# | FDR | Chromosome | Gene Symbol | Description | Absolute Fold Change |
|---|---|---|---|---|---|
| ENSGALT00000096799 | 0.045 | #N/A | #N/A | −45.54 | |
| ENSGALT00000087336 | 0.021 | 15 | CORO1C | coronin 1C (CORO1C) | −32.92 |
| ENSGALT00000077706 | 0.002 | 8 | PTPRF | protein tyrosine phosphatase, receptor type | −29.51 |
| ENSGALT00000081103 | 0 | 6 | PSAP | prosaposin | −27.67 |
| ENSGALT00000049779 | 0 | 9 | EIF4G1 | eukaryotic translation initiation factor 4 | −24.18 |
| ENSGALT00000087331 | 0.016 | 6 | microsemino protein beta | −22.96 | |
| ENSGALT00000078878 | 0.043 | #N/A | #N/A | −22.35 | |
| ENSGALT00000066511 | 0.023 | 2 | RPL7 | ribosomal protein L7 | −15.15 |
| ENSGALT00000064276 | 0.028 | 18 | TBCD | tubulin folding cofactor | −12.68 |
| ENSGALT00000018692 | 0 | 5 | EIF5 | eukaryotic translation initiation | −12.48 |
| ENSGALT00000096298 | 0.036 | 3 | SMAP1 | small ArfGAP 1 | −12.08 |
| ENSGALT00000021113 | 0 | 1 | DENND5B | DENN domain containing 5B | −10.93 |
| ENSGALT00000036292 | 0.005 | 12 | PRKCD | protein kinase C | −10.82 |
| ENSGALT00000098137 | 0 | 3 | SPTBN1 | spectrinbeta non-erythrocytic | −9.17 |
| ENSGALT00000101130 | 0 | 9 | PCYT1A | phosphate cytidylyltransferase 1, choline, alpha | −8.61 |
| ENSGALT00000047339 | 0.05 | 4 | SMAD1 | SMAD family member 1 | −8.45 |
| ENSGALT00000095523 | 0.007 | 4 | FAT1 | FAT atypical cadherin 1 | −8.33 |
| ENSGALT00000096470 | 0 | 2 | SLC4A7 | Solute carrier family4 member | −6.63 |
| ENSGALT00000107225 | 0 | 24 | APOA4 | apolipoprotein A4(APOA4) | −6.43 |
| ENSGALT00000055069 | 0.003 | 2 | SEMA5A | semaphorin 5A | −6.34 |
| ENSGALT00000007275 | 0.027 | 20 | NCOA3 | nuclear receptor coactivator 3 | −6.32 |
| ENSGALT00000090409 | 0.05 | 1 | TMCC3 | transmembrane and coiled-coil domain family | −5.76 |
| ENSGALT00000107684 | 0.001 | 6 | PDCD4 | programmed cell death 4 | −5.31 |
| ENSGALT00000015332 | 0.026 | 3 | BROX | BRO1 domain and CAAX motif | −4.73 |
| ENSGALT00000086950 | 0.023 | 2 | YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase | −4.63 |
| ENSGALT00000017711 | 0.045 | 7 | ABCB11 | ATP binding cassette subfamily B | −4.50 |
| ENSGALT00000022319 | 0.003 | 3 | GTF2H5 | general transcription factor | −4.37 |
| ENSGALT00000104993 | 0.009 | 8 | LMO4 | LIM domain only | −4.26 |
| ENSGALT00000004104 | 0.027 | 21 | CLSTN1 | Cal syntenin 1 (CLSTN1) | −3.90 |
| ENSGALT00000007773 | 0.002 | 15 | ISCU | iron-sulfur cluster assembly enzyme | −3.78 |
| ENSGALT00000061711 | 0.004 | 23 | PTP4A2 | protein tyrosine phosphatase type IVA, | −3.53 |
| ENSGALT00000006691 | 0.012 | 8 | SOAT1 | sterol O-acyltransferase 1 | −3.32 |
| ENSGALT00000032201 | 0.025 | 4 | HPGD | 15-hydroxyprostaglandin dehydrogenase (HPGD) | −3.23 |
| ENSGALT00000039749 | 0.001 | 1 | CD36 | CD36 molecule (CD36) | −3.15 |
| ENSGALT00000025653 | 0 | 3 | EEF1A1 | eukaryotic translation elongation factor 1 | −3.12 |
| ENSGALT00000105502 | 0.017 | #N/A | #N/A | −2.90 | |
| ENSGALT00000008547 | 0.001 | 9 | RBP2 | retinol binding protein | −2.90 |
| ENSGALT00000066968 | 0 | #N/A | #N/A | −2.83 | |
| ENSGALT00000063525 | 0.045 | 6 | CYP2C18 | cytochrome | −2.79 |
| ENSGALT00000018393 | 0.025 | 2 | RAB5A | RAB5A, member RAS | −2.74 |
| ENSGALT00000024116 | 0.026 | 3 | SOT3A1L | sulfotransferase family 3A | −2.56 |
| ENSGALT00000052923 | 0.023 | 11 | CA7 | carbonic anhydrase 7 | −2.54 |
| ENSGALT00000089467 | 0.049 | 16 | BF1 | MHC BF1 | −2.47 |
| ENSGALT00000019554 | 0.043 | 4 | FABP2 | fatty acid binding protein 2 | −2.45 |
| ENSGALT00000083719 | 0.012 | 2 | MEP1B | meprin A subunit beta | −2.39 |
| ENSGALT00000086032 | 0.028 | 1 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase | −2.33 |
| ENSGALT00000062517 | 0.035 | #N/A | #N/A | −2.21 | |
| ENSGALT00000004055 | 0.028 | 15 | RAN | RAN, member RAS | −2.15 |