Table 1.

Efficiency of various antibiotics in IBS treatment.

Antibiotic	Efficiency in IBS treatment
Tetracycline, Amoxicilline clavulanate, Metronidazole, Norfloxacine	Moderate effect on IBS symptoms Possible systemic side effects Many cases of clinical resistance High risk of Clostridioides difficile infection
Neomycin	Rapid and durable clinical resistance Weak effect on IBS symptoms
Rifaximin	Effective in improvement of IBS symptoms including abdominal pain, bloating and diarrhea Weak effect on constipated patients Affects the composition of gut microbiota Direct anti-inflammatory actions Low possibility of clinical resistance or Clostridioides difficile infection