TABLE 1.
Gene product | Level of expressiona with treatment
|
Accession no. | Result by Northern analysisb | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Ad-BG (12 h) | None | PTEN (3 h) | PTEN (6 h) | PTEN (9 h) | PTEN (12 h) | PTEN (15 h) | PTEN (18 h) | |||
IRS-2 | 101 | 2 | 2,462 | 2,356 | 1,265 | 1,208 | 1,957 | 1,910 | AA347674 | +++ |
HEF | −3 | 44 | 204 | 275 | 234 | 199 | 177 | 96 | L43821 | +++ |
DAF | 69 | 30 | 1,789 | 834 | 474 | 357 | 525 | 320 | AA424741 | ++ |
Zf9/Bcd | 212 | 490 | 2,303 | 782 | 544 | 506 | 1,002 | 1,128 | AA018922 | ++ |
Keratin 6B | 1,617 | 786 | 5,409 | 7,786 | 7,447 | 7,376 | 3,041 | 1,470 | AA026418 | + |
IR | 2 | 12 | 77 | 86 | 68 | 98 | 161 | 75 | X02160 | + |
H98071c | 262 | 262 | 2,551 | 1,386 | 400 | 479 | 878 | 1,305 | H98071 | + |
AA609795c | −2 | 3 | 357 | 204 | 266 | 312 | 350 | 345 | AA609795 | + |
Fluorescence units indicating absolute expression. Ad-BG, Ad-β-gal.
+, two- to threefold induction; ++, moderate induction detected above a low-level baseline; +++, very strong induction above a low-level baseline.
GenBank sequence accession number.