Table 2.

DEGs with betweenness centrality outer than 95% after z-score normalization.

Gene	AD	AD+COVID-19	Fold Change	Betweenness Centrality	Degree
RPS27A	911.74	1780.96	0.97	0.20	103
UBA52	677.56	1204.86	0.82	0.15	95
NCOR1	2542.38	3646.46	0.52	0.13	18
MAPK3	444.68	763.02	0.78	0.13	26
ESR1	74.27	19.81	−1.84	0.10	23
KRAS	673.02	411.00	−0.72	0.09	26
PTGES3	1154.09	676.38	−0.75	0.08	16
NCOR2	1127.04	2296.71	1.03	0.08	14
RB1	600.81	340.79	−0.81	0.07	16
SNW1	269.40	404.53	0.56	0.06	17
SEC13	228.79	131.39	−0.69	0.06	16
MAPK14	485.07	267.52	−0.84	0.06	18
TBL1XR1	2220.09	1191.37	−0.90	0.06	8
RAC1	948.07	1678.89	0.83	0.05	22
NCL	1784.81	6608.74	1.89	0.05	17
SRSF1	506.54	284.79	−0.78	0.05	19
PTPN11	2778.66	5429.21	0.97	0.04	16
DUT	237.24	152.47	−0.67	0.04	9
NCBP1	600.36	409.11	−0.58	0.04	14
POLR2A	1164.20	1595.16	0.45	0.04	22
ARRB1	1183.63	1826.55	0.62	0.04	10

Note: The fold change was computed as log₂(AD+COVID-19/AD). DEGs are sorted by betweenness centrality parameter. All the values are rounded to the second decimal digit.