Table 1.
Body weight, femur geometry, mechanical properties, and immature collagen content of fumonisin-intoxicated male and female rats. Data are presented as mean ± SE. Statistically significant differences between groups (at p < 0.05) are indicated by a and b.
| Dependent Variable | Sex | FBs [mg/kg b.w.] | p-Value | ||
|---|---|---|---|---|---|
| 0 | 60 | 90 | |||
| Body weight [g] | M | 10.050 ± 0.438 a | 6.819 ± 0.105 b | 6.839 ± 0.203 b | <0.001 |
| Femur length [mm] | 11.546 ± 0.068 a | 10.794 ± 0.245 b | 10.200 ± 0.214 b | <0.001 | |
| Cross-sectional area [mm2] | 4.148 ± 0.194 a | 3.935 ± 0.288 a,b | 3.250 ± 0.212 b | 0.034 | |
| Ultimate force [N] | 1.693 ± 0.058 a | 1.190 ± 0.096 b | 1.170 ± 0.028 b | <0.001 | |
| Stiffness [N/mm] | 5.590 ± 0.409 a | 3.050 ± 0.163 b | 3.060 ± 0.127 b | <0.001 | |
| Collagentrabecular [%] | 13.188 ± 1.782 a,b | 15.948 ± 1.867 a | 8.003 ± 0.434 b | 0.004 | |
| Collagencompact [%] | 20.051 ± 2.034 a | 7.589 ± 0.978 b | 17.365 ± 1.528 a | <0.001 | |
| Body weight [g] | F | 7.766 ± 0.202 a | 6.747 ± 0.215 a,b | 5.903 ± 0.427 b | 0.001 |
| Femur length [mm] | 10.929 ± 0.075 a | 9.870 ± 0.174 b | 9.769 ± 0.173 b | <0.001 | |
| Cross-sectional area [mm2] | 3.945 ± 0.219 a | 3.726 ± 0.283 a,b | 3.115 ± 0.142 b | 0.040 | |
| Ultimate force [N] | 1.434 ± 0.099 a | 1.104 ± 0.101 b | 1.212 ± 0.082 b | 0.012 | |
| Stiffness [N/mm] | 4.508 ± 0.743 | 2.636 ± 0.324 | 3.770 ± 0.405 | 0.065 | |
| Collagentrabecular [%] | 14.231 ± 1.144 a,b | 13.634 ± 0.661 a | 18.699 ± 1.967 b | 0.032 | |
| Collagencompact [%] | 8.283 ± 0.764 a | 17.041 ± 3.056 b | 18.165 ± 1.782 b | 0.006 | |
FBs, Fumonisins; SE, standard error; F, female; M, male.