Table 2.
Parameter | Tacrolimus C/D Ratio | p | |
---|---|---|---|
Slow Metabolizers ≥1.48 n = 61 |
Fast Metabolizers <1.48 n = 61 |
||
Baseline body composition analysis | |||
Weight (kg) | 74.9 (70.5–79.2) | 76.1 (72.4–79.7) | 0.67 |
ICW (L) | 24.5 (23.1–25.9) | 25.5 (24.1–26.9) | 0.31 |
ECW (L) | 15.7 (14.8–16.5) | 16.2 (15.3–17.0) | 0.42 |
TBW (L) | 40.2 (37.9–42.5) | 41.7 (39.4–44.0) | 0.35 |
ECW/TBW | 0.390 (0.387–0.393) | 0.388 (0.385–0.390) | 0.27 |
Phase angle (o) | 5.0 (4.8–5.3) | 5.2 (5.0–5.4) | 0.32 |
Visceral fat area (cm2) * | 93.6 (59.1–126.3) | 88.4 (51.5–129.9) | 0.60 |
LBM (kg) | 51.5 (48.6–54.4) | 53.5 (50.5–56.4) | 0.34 |
LBM (%) | 69.2 (67.0–71.4) | 70.5 (67.7–73.3) | 0.45 |
LBMI (kg/m2) | 18.6 (17.9–19.3) | 18.8 (18.2–19.5) | 0.62 |
Data presented as means with 95% confidence interval, * medians with Q1-Q3 values, as appropriate. C/D, concentration-to-dose; ICW, intracellular water; ECW, extracellular water; TBW, total body water; LBM, lean body mass; LBMI, lean body mass index.