Ab |
antibody |
ADCC |
antibody-dependent cellular cytotoxicity |
AIM2 |
absent in melanoma 2 |
AKT |
protein kinase |
AML |
acute myeloid leukemia |
AP-1 |
activator protein 1 |
APC |
antigen-presenting cell |
ATF |
activating transcription factor |
ATP |
adenosine triphosphate |
B2M |
β-2 microglobulin |
BATF |
basic leucine zipper transcription factor |
BCR |
B cell receptor |
Blimp-1 |
B lymphocyte-induced maturation protein-1 |
BTLA |
B and T lymphocyte attenuator |
BTN |
butyrophilin |
BTNL |
butyrophilin-like molecules |
CAF |
cancer-associated fibroblast |
CAR |
chimeric antigen receptor |
CBL |
casitas B-lineage lymphoma |
CCL |
CC-chemokine ligand |
cDC |
conventional dendritic cell |
CDS |
cytosolic DNA sensor |
CEACAM1/5/6 |
carcinoembryonic AG-related cell adhesion molecule 1/5/6 |
cGas |
cyclic GMP-AMP synthase |
CLEVER-1 |
common lymphatic endothelial and vascular endothelial receptor-1 |
CLR |
C-type lectin receptors |
cNK |
conventional natural killer cell |
COX |
cyclooxygenase |
CSF-1 |
Colony Stimulating Factor 1 |
CTA |
cancer/testis antigen |
CTLA-4 |
cytotoxic T-lymphocyte-associated protein 4 |
CXCL |
C-X-C motif chemokine |
DAI |
DNA-dependent activator of IRFs |
DAMP |
damage-associated molecular pattern |
DC |
dendritic cells |
DCIR |
C-type lectin dendritic cell (DC) immunoreceptor |
DC-SCRIPT |
dendritic cell-specific transcript |
DNA |
deoxyribonucleic Acid |
DNAM-1 |
DNAX accessory molecule-1 |
EAT2 |
ewing sarcoma-activated transcript 2 |
ECM |
extracellular matrix |
Eomes |
T-box brain protein 2 |
ER |
endoplasmatic reticulum |
ERK |
extracellular signal-regulated kinase |
ER-α |
nuclear estrogen receptor α |
FGF-2 |
basic fibroblast growth factor |
FGL1 |
fibrinogen-like protein 1 |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
FOXP3 |
forkhead box P3 |
GAPDH |
glyceraldehyde 3-phosphate dehydrogenase |
GARP |
glycoprotein-A repetitions predominant |
Gata3 |
GATA binding protein 3 |
GITR9 |
glucocorticoid-induced TNFR-related protein 9 |
GM-CSF |
granulocyte-macrophage colony-stimulating factor |
HCC |
hepatocellular carcinoma |
HERV |
human genome consists of endogenous retroviruses |
HIF-1a |
hypoxia-inducible factor 1-alpha |
HLA-DR |
human leukocyte antigen—DR isotype |
HLA |
human leukocyte antigen |
HMGB1 |
high mobility group box 1 |
HVEM |
herpes virus entry mediator |
ICAM |
intercellular adhesion molecule |
ICB |
immune checkpoint blockade |
ICOS |
inducible T cell co-stimulator |
IDO |
indoleamine-pyrrole 2,3-dioxygenase |
IFN |
interferon |
Ig |
immunoglobulin |
IKAROS |
ikaros family zinc finger protein 1 |
IL |
interleukin |
ILT2/4 |
immunoglobulin-like transcript 2/4 |
iNOS |
inducible nitric oxide synthases |
IRF |
interferon regulatory factor |
JAK |
janus kinase |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
KIR2DL4 |
killer immunoglobulin-like receptor (KIR) 2DL4 |
KIR3DL2 |
killer cell immunoglobulin-like receptor (KIR) 3DL2 |
KLRG-1 |
killer cell lectin like receptor G1 |
LAG-3 |
lymphocyte activation gene 3 |
LGP2 |
laboratory of genetics and physiology 2 |
LIGHT/TNFSF14 |
tumor necrosis factor superfamily member 14 |
LIF |
leukemia inhibitory factor |
lncRNA |
long non-coding RNA |
LPS |
lipopolysaccharides |
LTα |
lymphotoxin α |
mAb |
monoclonale antibody |
Maf |
musculoaponeurotic fibrosarcoma |
MAPK |
mitogen activated protein kinases |
MDA5 |
melanoma differentiation-associated protein 5 |
MDSC |
myeloid-derived suppressor cells |
MHC |
major histocompatibility complex |
MICL |
myeloid inhibitory C-type lectin-like receptor |
Mincle |
macrophage inducible Ca2+-dependent lectin receptor |
MMP9 |
matrix metallopeptidase 9 |
mTOR |
mammalian target of rapamycin complex 1 |
MYC |
myelocytomatosis oncogene |
MyD88 |
myeloid differentiation primary response 88 |
Necls |
nectin and nectin-like molecules |
NFAT |
nuclear factor of activated T cells |
NF-КB |
nuclear factor kappa light chain enhancer of activated B cells |
NK cell |
natural killer cell |
NKG2A |
natural killer group 2A |
NKX2-1-AS1 |
NKX2-1 antisense RNA 1 |
NLR |
nucleotide binding oligomerization domain-like receptor |
NLRC5 |
NOD-like receptor family CARD domain containing 5 |
NO |
nitrogen monoxide |
NR2F2/6 |
nuclear receptor subfamily 2 group F member 2/6 |
NR4A |
nuclear receptor 4A |
NSCLC |
non-small cell lung cancer |
PAMP |
pathogen-associated molecular pattern |
PC |
plasma cell |
PCPB1 |
poly(rC)-binding protein 1 |
PD-1 |
programmed cell death protein 1 |
PD-L1 |
programmed cell death 1 ligand 1 |
PD-L2 |
programmed cell death 1 ligand 2 |
PGE |
prostaglandin E synthase |
PI3K |
phosphatidylinositol-3-kinase |
PKC |
protein kinase C |
PLXNB1/2 |
plexin B1/2 |
Prdm1 |
PR domain zinc finger protein 1 |
PRR |
pattern recognition receptors |
PS |
phosphatidylserine |
PtdSer |
phosphatidylserine |
PVRIG |
poliovirus receptor related immunoglobulin |
RIG-I |
retinoic acid-inducible gene I |
RGS-5 |
regulator of G-protein signaling-5 |
RLR |
retinoic acid-inducible gene I (RIG-I)-like receptors |
RORγt |
RAR-related orphan receptor gamma |
ROS |
reactive oxygen species |
SAP |
SLAM-associated protein |
SEMA3A/3B/4D |
semaphorin 3A/3B/4D |
SIRPα |
signal regulatory protein α |
Sirt1 |
regulatory protein SIR2 homolog |
SLAMF4 |
signaling lymphocyte activation molecule F4 |
STAT |
signal transducer and activator of transcription |
STING |
stimulator of interferon genes |
TAM |
tumor-associated macrophages |
TAMC |
tumor-associated mast cell |
TAN |
tumor-associated neutrophils |
TAP1/2 |
antigen processing 1/2 |
T-bet |
T-box expressed in T cells |
TCR |
T cell receptor |
TDO |
tryptophan-2,3-dioxygenase |
Tfh cells |
follicular helper T cells |
TGF |
transforming growth factor |
Th cells |
T helper cells |
TIGIT |
T cell immunoreceptor with Ig and ITIM domains |
TILs |
tumor-infiltrating lymphocytes |
TIM-3 |
T cell immunoglobulin domain and mucin domain containing protein-3 |
TLR |
toll-like receptor |
TME |
tumor microenvironment |
TNF |
tumor necrosis factor |
TNFR |
tumor necrosis factor receptor |
TOX |
thymocyte selection-associated HMG BOX |
Tregs |
regulatory T cells |
VEGF |
vascular endothelial growth factor |
VISTA |
V-domain immunoglobulin suppressor of T cell activation |
VSIG-3 |
V-Set and immunoglobulin domain-containing protein 3 |
Wnt |
wingless-related integration site |