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. 2021 Dec 10;22(24):13311. doi: 10.3390/ijms222413311
Ab antibody
ADCC antibody-dependent cellular cytotoxicity
AIM2 absent in melanoma 2
AKT protein kinase
AML acute myeloid leukemia
AP-1 activator protein 1
APC antigen-presenting cell
ATF activating transcription factor
ATP adenosine triphosphate
B2M β-2 microglobulin
BATF basic leucine zipper transcription factor
BCR B cell receptor
Blimp-1 B lymphocyte-induced maturation protein-1
BTLA B and T lymphocyte attenuator
BTN butyrophilin
BTNL butyrophilin-like molecules
CAF cancer-associated fibroblast
CAR chimeric antigen receptor
CBL casitas B-lineage lymphoma
CCL CC-chemokine ligand
cDC conventional dendritic cell
CDS cytosolic DNA sensor
CEACAM1/5/6 carcinoembryonic AG-related cell adhesion molecule 1/5/6
cGas cyclic GMP-AMP synthase
CLEVER-1 common lymphatic endothelial and vascular endothelial receptor-1
CLR C-type lectin receptors
cNK conventional natural killer cell
COX cyclooxygenase
CSF-1 Colony Stimulating Factor 1
CTA cancer/testis antigen
CTLA-4 cytotoxic T-lymphocyte-associated protein 4
CXCL C-X-C motif chemokine
DAI DNA-dependent activator of IRFs
DAMP damage-associated molecular pattern
DC dendritic cells
DCIR C-type lectin dendritic cell (DC) immunoreceptor
DC-SCRIPT dendritic cell-specific transcript
DNA deoxyribonucleic Acid
DNAM-1 DNAX accessory molecule-1
EAT2 ewing sarcoma-activated transcript 2
ECM extracellular matrix
Eomes T-box brain protein 2
ER endoplasmatic reticulum
ERK extracellular signal-regulated kinase
ER-α nuclear estrogen receptor α
FGF-2 basic fibroblast growth factor
FGL1 fibrinogen-like protein 1
Fos Fos proto-oncogene, AP-1 transcription factor subunit
FOXP3 forkhead box P3
GAPDH glyceraldehyde 3-phosphate dehydrogenase
GARP glycoprotein-A repetitions predominant
Gata3 GATA binding protein 3
GITR9 glucocorticoid-induced TNFR-related protein 9
GM-CSF granulocyte-macrophage colony-stimulating factor
HCC hepatocellular carcinoma
HERV human genome consists of endogenous retroviruses
HIF-1a hypoxia-inducible factor 1-alpha
HLA-DR human leukocyte antigen—DR isotype
HLA human leukocyte antigen
HMGB1 high mobility group box 1
HVEM herpes virus entry mediator
ICAM intercellular adhesion molecule
ICB immune checkpoint blockade
ICOS inducible T cell co-stimulator
IDO indoleamine-pyrrole 2,3-dioxygenase
IFN interferon
Ig immunoglobulin
IKAROS ikaros family zinc finger protein 1
IL interleukin
ILT2/4 immunoglobulin-like transcript 2/4
iNOS inducible nitric oxide synthases
IRF interferon regulatory factor
JAK janus kinase
Jun Jun proto-oncogene, AP-1 transcription factor subunit
KIR2DL4 killer immunoglobulin-like receptor (KIR) 2DL4
KIR3DL2 killer cell immunoglobulin-like receptor (KIR) 3DL2
KLRG-1 killer cell lectin like receptor G1
LAG-3 lymphocyte activation gene 3
LGP2 laboratory of genetics and physiology 2
LIGHT/TNFSF14 tumor necrosis factor superfamily member 14
LIF leukemia inhibitory factor
lncRNA long non-coding RNA
LPS lipopolysaccharides
LTα lymphotoxin α
mAb monoclonale antibody
Maf musculoaponeurotic fibrosarcoma
MAPK mitogen activated protein kinases
MDA5 melanoma differentiation-associated protein 5
MDSC myeloid-derived suppressor cells
MHC major histocompatibility complex
MICL myeloid inhibitory C-type lectin-like receptor
Mincle macrophage inducible Ca2+-dependent lectin receptor
MMP9 matrix metallopeptidase 9
mTOR mammalian target of rapamycin complex 1
MYC myelocytomatosis oncogene
MyD88 myeloid differentiation primary response 88
Necls nectin and nectin-like molecules
NFAT nuclear factor of activated T cells
NF-КB nuclear factor kappa light chain enhancer of activated B cells
NK cell natural killer cell
NKG2A natural killer group 2A
NKX2-1-AS1 NKX2-1 antisense RNA 1
NLR nucleotide binding oligomerization domain-like receptor
NLRC5 NOD-like receptor family CARD domain containing 5
NO nitrogen monoxide
NR2F2/6 nuclear receptor subfamily 2 group F member 2/6
NR4A nuclear receptor 4A
NSCLC non-small cell lung cancer
PAMP pathogen-associated molecular pattern
PC plasma cell
PCPB1 poly(rC)-binding protein 1
PD-1 programmed cell death protein 1
PD-L1 programmed cell death 1 ligand 1
PD-L2 programmed cell death 1 ligand 2
PGE prostaglandin E synthase
PI3K phosphatidylinositol-3-kinase
PKC protein kinase C
PLXNB1/2 plexin B1/2
Prdm1 PR domain zinc finger protein 1
PRR pattern recognition receptors
PS phosphatidylserine
PtdSer phosphatidylserine
PVRIG poliovirus receptor related immunoglobulin
RIG-I retinoic acid-inducible gene I
RGS-5 regulator of G-protein signaling-5
RLR retinoic acid-inducible gene I (RIG-I)-like receptors
RORγt RAR-related orphan receptor gamma
ROS reactive oxygen species
SAP SLAM-associated protein
SEMA3A/3B/4D semaphorin 3A/3B/4D
SIRPα signal regulatory protein α
Sirt1 regulatory protein SIR2 homolog
SLAMF4 signaling lymphocyte activation molecule F4
STAT signal transducer and activator of transcription
STING stimulator of interferon genes
TAM tumor-associated macrophages
TAMC tumor-associated mast cell
TAN tumor-associated neutrophils
TAP1/2 antigen processing 1/2
T-bet T-box expressed in T cells
TCR T cell receptor
TDO tryptophan-2,3-dioxygenase
Tfh cells follicular helper T cells
TGF transforming growth factor
Th cells T helper cells
TIGIT T cell immunoreceptor with Ig and ITIM domains
TILs tumor-infiltrating lymphocytes
TIM-3 T cell immunoglobulin domain and mucin domain containing protein-3
TLR toll-like receptor
TME tumor microenvironment
TNF tumor necrosis factor
TNFR tumor necrosis factor receptor
TOX thymocyte selection-associated HMG BOX
Tregs regulatory T cells
VEGF vascular endothelial growth factor
VISTA V-domain immunoglobulin suppressor of T cell activation
VSIG-3 V-Set and immunoglobulin domain-containing protein 3
Wnt wingless-related integration site