TC28a2cell line. (A) Group RuV, (B) GO group, (C) RuV group, (D) GO + RuV group. Visible changes in cell morphology after administration of virus and graphene +virus. In TC28a2 (C and D picture) cell line after 48 h after virus and graphene + virus administration increased cytopathic effect was noted. Note numerous changes in cell morphology after virus administration and reduced positive cells number in response to DAPI after 48 h (red arrow). The positive cells are located in colonies among cytopathic cells (D picture). Graphene positive cells maintain the shape of the TC28a2 cell line. DAPI + Rhodamine B. A and B—Mag 200x, C—40x, D—100x.